Hello and welcome to the Dark Kinase Knowledge Base. This website will serve as a test bed for ideas concerning how to display and collate information concerning understudied kinases.

This website focuses on the work associated with the Kinase IDG based at the University of North Carolina, Washington University at St Louis and Harvard. This consortium is focused on developing a better understanding of the approximately 160 kinases where their function in human biology is poorly understood. During the first stages of this project, we are focusing on five kinases.

Focus Kinases

In addition to this website, there are also several stand-alone tools associated with this project.

How to Cite the DKK

The dark kinase knowledgebase has been published in Nucleic Acids Research:

Berginski ME, Moret N, Liu C, Goldfarb D, Sorger PK, Gomez SM. The Dark Kinase Knowledgebase: an online compendium of knowledge and experimental results of understudied kinases. Nucleic Acids Research, 2021 Available Here